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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
19.09
Human Site:
S125
Identified Species:
30
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S125
A
E
R
N
I
L
E
S
V
K
H
P
F
I
V
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S125
A
E
R
N
I
L
E
S
V
K
H
P
F
I
V
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
S152
A
E
R
N
I
L
E
S
V
K
H
P
F
I
V
Dog
Lupus familis
XP_851971
482
53401
S123
A
E
R
N
I
L
E
S
V
K
H
P
F
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
S125
A
E
R
N
I
L
E
S
V
K
H
P
F
I
V
Rat
Rattus norvegicus
P67999
525
59113
E149
A
E
R
N
I
L
E
E
V
K
H
P
F
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
E106
A
E
R
N
I
L
E
E
V
K
H
P
F
I
V
Chicken
Gallus gallus
P18652
752
84421
D136
I
E
R
D
I
L
A
D
V
N
H
P
F
V
V
Frog
Xenopus laevis
P10665
733
82620
D118
M
E
R
D
I
L
A
D
V
H
H
P
F
V
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
E123
M
E
R
D
I
L
V
E
V
N
H
P
F
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
I320
E
R
V
V
L
E
A
I
Q
R
N
P
F
L
V
Honey Bee
Apis mellifera
XP_395876
456
51514
A127
A
E
R
N
I
L
E
A
V
K
H
P
F
I
V
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
H160
L
E
R
N
I
L
A
H
I
S
H
P
F
I
V
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
A130
A
E
R
N
I
L
E
A
V
Q
H
P
F
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S117
I
K
E
N
D
E
F
S
G
N
D
D
T
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
60
60
66.6
N.A.
20
93.3
66.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
73.3
73.3
73.3
N.A.
46.6
100
73.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
0
0
27
14
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
7
0
0
14
0
0
7
7
0
7
0
% D
% Glu:
7
87
7
0
0
14
60
20
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
94
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
87
0
0
0
0
% H
% Ile:
14
0
0
0
87
0
0
7
7
0
0
0
0
74
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
54
0
0
0
0
0
% K
% Leu:
7
0
0
0
7
87
0
0
0
0
0
0
0
7
0
% L
% Met:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
74
0
0
0
0
0
20
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
94
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
0
7
87
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
40
0
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
7
7
0
0
7
0
80
0
0
0
0
14
94
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _